Omics and the molecular exercise physiology.
| Autor: | Gomes C; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Almeida JA; Research in Exercise and Nutrition of Health and Sports Performance-PENSARE, Graduate Program in Movement Sciences, Federal University of Mato Grosso do Sul, Campo Grande, Brazil; Graduate Program in Health and Development in the Midwest Region, Faculty of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Brazil., Franco OL; Centro de Análises Proteômicas e Bioquímicas, Pós-Graduação em Ciências Genômicas e Biotecnologia Universidade Católica de Brasília, Brasília, Brazil; S-INOVA Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande, Mato Grosso Do Sul, Brazil., Petriz B; Postgraduate Program in Health Promotion, University of Franca (Unifran), Franca, São Paulo, Brazil; Laboratory of Molecular Exercise Physiology-University Center UDF, Brasília, Brazil. Electronic address: bernardopetriz@gmail.com. |
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| Jazyk: | angličtina |
| Zdroj: | Advances in clinical chemistry [Adv Clin Chem] 2020; Vol. 96, pp. 55-84. Date of Electronic Publication: 2019 Dec 18. |
| DOI: | 10.1016/bs.acc.2019.11.003 |
| Abstrakt: | Exercise is a well-known non-pharmacologic agent used to prevent and treat a wide range of pathologic conditions such as metabolic and cardiovascular disease. In this sense, the classic field of exercise physiology has determined the main theoretical and practical bases of physiologic adaptations in response to exercise. However, the last decades were marked by significant advances in analytical laboratory techniques, where the field of biochemistry, genetics and molecular biology promoted exercise science to enter a new era. Regardless of its application, whether in the field of disease prevention or performance, the association of molecular biology with exercise physiology has been fundamental for unveiling knowledge of the molecular mechanisms related to the adaptation to exercise. This chapter will address the natural evolution of exercise physiology toward genetics and molecular biology, emphasizing the collection of integrated analytical approaches that composes the OMICS and their contribution to the field of molecular exercise physiology. (© 2020 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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