Atypical lymphoid hyperplasia in a patient undergoing tonsillectomy for severe obstructive sleep apnea.

Autor: Kinealy BP; University of Missouri School of Medicine, Columbia, MO, USA., Harding BC; Department Otolaryngology-Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO, USA., Vazmitsel MA; Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO, USA., Laziuk K; Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO, USA., Gov-Ari E; Department Otolaryngology-Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO, USA. Electronic address: govarie@health.missouri.edu.
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2020 Jul; Vol. 134, pp. 110066. Date of Electronic Publication: 2020 Apr 24.
DOI: 10.1016/j.ijporl.2020.110066
Abstrakt: Tonsillectomy is a common procedure in the pediatric population, with subsequent microscopic examination of the specimen for cancer and other rare diagnoses occurring routinely. A 17 year-old female with a history of autoimmune vasculitis underwent adenotonsillectomy for severe obstructive sleep apnea. Pathology demonstrated small, medium and large lymphocytes and plasma cells obscuring the lymphoid follicles and germinal centers, with few Epstein-Barr virus positive lymphocytes. Tingible body macrophages were seen in the vaguely nodular areas. This reactive histologic pattern represents an atypical lymphoproliferative disorder never before documented in tonsils. Histopathologic images will be shown.
(Copyright © 2020. Published by Elsevier B.V.)
Databáze: MEDLINE
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