| Autor: |
Han J; Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. p.l.horvatovich@rug.nl., Sun J, Song S, Beljaars L, Groothuis GMM, Permentier H, Bischoff R, Halmos GB, Verhoeven CJ, Amstalden van Hove ER, Horvatovich P, Casini A |
| Jazyk: |
angličtina |
| Zdroj: |
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Jun 04; Vol. 56 (44), pp. 5941-5944. Date of Electronic Publication: 2020 Apr 29. |
| DOI: |
10.1039/d0cc00774a |
| Abstrakt: |
Targeted epitope-based mass spectrometry imaging (MSI) utilizes laser cleavable mass-tags bound to targeting moieties for detecting proteins in tissue sections. Our work constitutes the first proof-of-concept of a novel laser desorption ionization (LDI)-MSI strategy using photocleavable Ru(ii) polypyridine complexes as mass-tags for imaging of integrins αvβ3 in human cancer tissues. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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