Prevalence of hepatitis B and anti-hepatitis C virus antibody among people who inject drugs in the Lebanese population.

Autor: Rached AA; Faculty of Medical Science, Lebanese University, Hadath, Lebanon.; Ministry of Public Health, Beirut, Lebanon., Nakhoul M; Faculty of Medical Science, Lebanese University, Hadath, Lebanon., Richa C; Faculty of Medical Science, Lebanese University, Hadath, Lebanon., Jreij A; Faculty of Medical Science, Lebanese University, Hadath, Lebanon., Hanna PA; Faculty of Medical Science, Lebanese University, Hadath, Lebanon., Ammar W; Ministry of Public Health, Beirut, Lebanon.
Jazyk: angličtina
Zdroj: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit [East Mediterr Health J] 2020 Apr 16; Vol. 26 (4), pp. 461-467. Date of Electronic Publication: 2020 Apr 16.
DOI: 10.26719/emhj.19.094
Abstrakt: Background: People who inject drugs (PWIDs) are prone to a number of blood-borne viral infections. Hepatitis B virus (HBV) and hepatitis C virus (HCV) constitute an important public health concern in this high risk group.
Aims: We aimed to determine the prevalence of HBV and HCV antibody among PWIDs in Lebanon.
Methods: We conducted a prospective cross-sectional study between June 2015 and June 2016 on PWIDs recruited through Lebanese nongovernmental organizations in collaboration with the Lebanese Ministry of Public Health. The participants were tested for HBs antigen and HCV antibody using rapid test kits. The prevalence of each virus was then calculated. The correlation between both infections and other possible risk factors was also analysed.
Results: A total of 250 people were included in our study, of whom 98% were males. Mean age was 31.9 (standard deviation 8.7) years. The prevalence of HBsAg and anti-HCV among PWIDs was 1.2% and 15.6%, respectively. Older age, longer duration of drug use and lack of awareness were significantly correlated with a higher rate of HCV infection (P < 0.01). The high rate of needle sharing among our PWIDs significantly affected the prevalence of anti-HCVAb.
Conclusion: PWIDs remain the subpopulation most affected with chronic HCV in Lebanon.
(Copyright © World Health Organization (WHO) 2020. Open Access. Some rights reserved. This work is available under the CC BY-NC-SA 3.0 IGO license (https://creativecommons.org/licenses/by-nc-sa/3.0/igo).)
Databáze: MEDLINE