Translating the language of giants: translation-related genes as a major contribution of giant viruses to the virosphere.

Autor: Rodrigues RAL; Department of Microbiology, Federal University of Minas Gerais, Belo Horizonte, Brazil.; Department of Biological Sciences, Federal University of Ouro Preto, Ouro Preto, Brazil., da Silva LCF; Department of Microbiology, Federal University of Minas Gerais, Belo Horizonte, Brazil., Abrahão JS; Department of Microbiology, Federal University of Minas Gerais, Belo Horizonte, Brazil. jonatas.abrahao@gmail.com.
Jazyk: angličtina
Zdroj: Archives of virology [Arch Virol] 2020 Jun; Vol. 165 (6), pp. 1267-1278. Date of Electronic Publication: 2020 Apr 24.
DOI: 10.1007/s00705-020-04626-2
Abstrakt: Giant viruses of amoebas are a remarkable group of viruses. In addition to their large size and peculiar structures, the genetic content of these viruses is also special. Among the genetic features of these viruses that stand out is the presence of coding regions for elements involved in translation, a complex biological process that occurs in cellular organisms. No viral genome described so far has such a complex genetic arsenal as those of giant viruses, which code for several of these elements. Currently, tupanviruses have the most complete set of translation genes in the known virosphere. In this review, we have condensed what is currently known about translation genes in different groups of giant viruses and theorize about their biological importance, origin, and evolution, and what might possibly be found in the coming years.
Databáze: MEDLINE
Externí odkaz: