Early-Life Gut Microbiome-The Importance of Maternal and Infant Factors in Its Establishment.

Autor: Kapourchali FR; Department of Inflammation and Immunity, Cleveland Clinic, Cleveland, Ohio, USA., Cresci GAM; Department of Inflammation and Immunity, Cleveland Clinic, Cleveland, Ohio, USA.; Department of Pediatric Gastroenterology, Cleveland Clinic, Cleveland, Ohio, USA.; Center for Human Nutrition, Cleveland Clinic, Cleveland, Ohio, USA.
Jazyk: angličtina
Zdroj: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition [Nutr Clin Pract] 2020 Jun; Vol. 35 (3), pp. 386-405. Date of Electronic Publication: 2020 Apr 24.
DOI: 10.1002/ncp.10490
Abstrakt: The early-life microbiome is gaining appreciation as a major influencer in human development and long-term health. Multiple factors are known to influence the initial colonization, development, and function of the neonatal gut microbiome. In addition, alterations in early-life gut microbial composition is associated with several chronic health conditions such as obesity, asthma, and allergies. In this review, we focus on both maternal and infant factors known to influence early-life gut colonization. Also reviewed is the important role of infant feeding, including evidence-based strategies for maternal and infant supplementation with the goal to protect and/or restore the infant gut microbiome.
(© 2020 American Society for Parenteral and Enteral Nutrition.)
Databáze: MEDLINE
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