| Autor: |
Makhmudiyarova N; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Ufa 450075, Russia., Ishmukhametova I; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Ufa 450075, Russia., Dzhemileva L; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Ufa 450075, Russia., D'yakonov V; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Ufa 450075, Russia., Ibragimov A; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Ufa 450075, Russia., Dzhemilev U; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Ufa 450075, Russia. |
| Abstrakt: |
An efficient method for the synthesis of tetraoxathiaspiroalkanes, tetraoxathiocanes, and hexaoxathiadispiroalkanes was developed by reactions of pentaoxacanes, pentaoxaspiroalkanes, and heptaoxadispiroalkanes with hydrogen sulfide in the presence of a catalyst, Sm(NO 3 ) 3 ·6H 2 O. We found that the synthesized S-containing di- and triperoxides exhibit high cytotoxic activity against Jurkat, K562, U937, and HL60 tumor cultures, and fibroblasts. |
