Quality of life is not affected by thyroid surgery in nontoxic benign goitre in long-term surveillance-A prospective observational study.

Autor: Tabriz N; University Hospital for Visceral Surgery Medical Campus University of Oldenburg Pius-Hospital Oldenburg Germany., Uslar VN; University Hospital for Visceral Surgery Medical Campus University of Oldenburg Pius-Hospital Oldenburg Germany., Tabriz I; University Hospital for Visceral Surgery Medical Campus University of Oldenburg Pius-Hospital Oldenburg Germany., Weyhe D; University Hospital for Visceral Surgery Medical Campus University of Oldenburg Pius-Hospital Oldenburg Germany.
Jazyk: angličtina
Zdroj: Endocrinology, diabetes & metabolism [Endocrinol Diabetes Metab] 2020 Feb 26; Vol. 3 (2), pp. e00115. Date of Electronic Publication: 2020 Feb 26 (Print Publication: 2020).
DOI: 10.1002/edm2.115
Abstrakt: Objective: Quality of life (QoL) has so far seldom been taken into account by default in decision-making for surgical indication in thyroid surgery. Therefore, we compared pre- and postoperative QoL of patients using the EuroQoL-5D (EQ-5D) questionnaire. The influence of certain socio-economic factors on QoL as a second end-point was considered.
Design: Prospective cohort study.
Patients: About 153 patients with euthyroid symptomatic benign goitre after hemi- and total thyroidectomy (follow-up 83.6%) have been included.
Measurements: The EQ-5D questionnaire was used prior to and 1 year after surgery. In addition, a questionnaire for assessment of socio-economic status was collected.
Results: For n = 90 (n = 67 female, n = 23 male), total thyroidectomy (TT) and, for n = 63 (n = 45 female, n = 18 male), hemithyroidectomy (HT) were performed. None permanent dysfunction of the vocal cord was recorded. Transient symptomatic hypocalcaemia was detected in 9% of the thyroidectomy group (8/90 patients). At follow-up, 86% of patients showed either no change or improved QoL. About 14% of patients complained of deteriorated QoL, regardless of the extent of surgery. Socio-economic factors did not influence postoperative QoL.
Conclusions: Results indicate that in pre-operative consultation of patients with benign goitre, the improvement of QoL should be taken into account for decision-making in cases of ambiguous surgical indication. Contrary to current discussions that too much thyroid surgery is performed in Germany, we can recommend presenting surgery as an equivalent option to watchful waiting as QoL is at least preserved or improved. The extension of the resection should, however, be decided individually.
Competing Interests: The authors declare no commercial interest or conflict of interest in the subject of this study.
(© 2020 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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