Use of PET/CT to aid clinical decision-making in cases of solitary pulmonary nodule: a probabilistic approach.

Autor: Mourato FA; Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil., Brito AET; Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil., Romão MSC; Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil., Santos RGG; Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil., de Almeida CA; Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil., de Almeida Filho PJ; Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil., Leal ALG; Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil.
Jazyk: angličtina
Zdroj: Radiologia brasileira [Radiol Bras] 2020 Jan-Feb; Vol. 53 (1), pp. 1-6.
DOI: 10.1590/0100-3984.2019.0034
Abstrakt: Objective: To determine the frequency with which 18 F-FDG-PET/CT findings change the probability of malignancy classification of solitary pulmonary nodules.
Materials and Methods: This was a retrospective analysis of all 18 F-FDG-PET/CT examinations performed for the investigation of a solitary pulmonary nodule between May 2016 and May 2017. We reviewed medical records and PET/CT images to collect the data necessary to calculate the pre-test probability of malignancy using the Swensen model and the Herder model. The probability of malignancy was classified as low if < 5%, intermediate if 5-65%, and high if > 65%. Cases classified as intermediate in the Swensen model were reclassified by the Herder model.
Results: We reviewed the records for 33 patients, of whom 17 (51.5%) were male. The mean age was 68.63 ± 12.20 years. According to the Swensen model, the probability of malignancy was intermediate in 23 cases (69.7%). Among those, the application of the Herder model resulted in the probability of malignancy being reclassified as low in 6 (26.1%) and as high in 8 (34.8%).
Conclusion: 18 F-FDG-PET/CT was able to modify the probability of malignancy classification of a solitary pulmonary nodule in more than 50% of the cases evaluated.
Databáze: MEDLINE
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