Characterization of Hearing Loss in Adult Patients With Nondialysis Chronic Kidney Disease.

Autor:	Lara-Sánchez H; Otology Unit., Calvo DH; Audiology and Otology Unit., Sañudo EG; Otology Unit., Mayo-Iscar A; Department of Statistics and Operational Research.; Mathematics Institute (IMUVA), Valladolid University., Cordero MEP; Nephrology Department., Monfá-Bosch JM; Nephrology Department., Valdezate LÁV; Otolaryngology Head and Neck Surgery Department, Río Hortega University Hospital, Valladolid, Spain.
Jazyk:	angličtina
Zdroj:	Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology [Otol Neurotol] 2020 Aug; Vol. 41 (7), pp. e776-e782.
DOI:	10.1097/MAO.0000000000002656
Abstrakt:	Objective: To confirm the association between chronic kidney disease and sensorineural hearing loss in non-dialysis non-diabetic patients and to establish the audiological profile of these patients indicating the possible location of the auditory damage. Study Design: Cross-sectional study. Setting: Tertiary referral center. Patients: Patients between 18 and 60 years old with chronic kidney disease, without diabetes mellitus and without personal history of otology disease, were compared with a healthy control group pared by sex and age to establish differences between their audiological profile. Interventions: Pure tone audiometry (PTA), transient evoked otoacoustic emissions (TEOAEs), distortion products otoacoustic emissions (DPOAEs), and auditory brainstem responses (ABR) were performed in both groups. Main Outcome Measures: Mean and standard deviation of PTA auditory thresholds, TEOAEs reproducibility, DPOAEs level/noise, and ABR absolute latency and interwave latency were measured, and compared using linear mixed models. Results: Fifty one cases were included and compared with 51 healthy volunteers. The audiometric profile found in patients with chronic kidney disease was a sensorineural hearing loss in 4 to 8 kHz frequencies in the PTA, a decrease in the TEOAEs reproducibility and a decrease in the DPOAEs level. An enlargement in the V wave absolute latency and III to V and I to V interwave latency in the ABR were also found but within normal range. Conclusions: There is an association between chronic kidney disease in non-dialysis non diabetic adults patients and sensorineural hearing loss, affecting high frequencies and having the cochlea as the main site of auditory damage.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu