A case of adult-onset tubulointerstitial nephritis and uveitis syndrome presenting with granulomatous panuveitis.

Autor: Tekin K; Department of Ophthalmology, Ercis State Hospital, Van, Turkey., Erol YO; Department of Uveal Diseases, Ankara Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Kurtulan O; Department of Pathology, Hacettepe University, Ankara, Turkey., Baydar DE; Department of Pathology, Hacettepe University, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Taiwan journal of ophthalmology [Taiwan J Ophthalmol] 2020 Mar 04; Vol. 10 (1), pp. 66-70. Date of Electronic Publication: 2020 Mar 04 (Print Publication: 2020).
DOI: 10.4103/tjo.tjo_33_18
Abstrakt: The tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disorder that is probably underdiagnosed in clinical practice. Ocular involvement in TINU syndrome not only presents with the nongranulomatous anterior uveitis in 80% of patients but also manifests as intermediate, posterior, or panuveitis. This case report mentions an adult male patient who presented with granulomatous iridocyclitis with panuveitis and mild renal insufficiency. Workup for connective tissue and infectious diseases was negative for the patient. He was diagnosed with TINU syndrome based on the findings of renal biopsy. Both the uveitis and nephritis promptly responded well to steroid treatment, and there was no recurrence during the follow-up of 24 months.
Competing Interests: The authors declare that there are no conflicts of interests of this paper.
(Copyright: © 2020 Taiwan J Ophthalmol.)
Databáze: MEDLINE