High-resolution tandem mass spectrometry dataset reveals fragmentation patterns of cardiac glycosides in leaves of the foxglove plants.
| Autor: | Ravi BG; Department of Biological Sciences, University at Buffalo, State University of New York, Buffalo, NY 14260, United States., Guardian MGE; Department of Chemistry, Chemistry Instrumentation Center, University at Buffalo, State University of New York, Buffalo, NY 14260, United States., Dickman R; Department of Chemistry, Chemistry Instrumentation Center, University at Buffalo, State University of New York, Buffalo, NY 14260, United States., Wang ZQ; Department of Biological Sciences, University at Buffalo, State University of New York, Buffalo, NY 14260, United States. |
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| Jazyk: | angličtina |
| Zdroj: | Data in brief [Data Brief] 2020 Mar 20; Vol. 30, pp. 105464. Date of Electronic Publication: 2020 Mar 20 (Print Publication: 2020). |
| DOI: | 10.1016/j.dib.2020.105464 |
| Abstrakt: | Cardiac glycosides, steroid derivatives extracted from the foxglove plants, have been used for the treatment of heart failure since the 18th century. A method based on liquid chromatography coupled with high-resolution tandem mass spectrometry (LC/MS 2 ) has been developed to characterize and quantify cardiac glycosides in fresh-leaf extracts of the foxglove ( Digitalis sp. ) plants [1]. In this report, the fragmentation spectra of additional authentic standards of cardiac glycoside (digitoxigenin, digoxigenin, β -acetyldigoxin) and cardenolides identified in the leaves of Digitalis lanata ( D. lanata ) and Digitalis purpurea ( D. purpurea ) were provided with high resolution. The exact mass of signature peaks for the aglycones and the sugar units of cardenolides were measured. This dataset is valuable to researchers interested in characterizing cardenolides in plants, or quantifying cardenolides in drug tablets, or studying cardenolide toxicities in animals. The fragmentation patterns of authentic cardenolide standards provided in these data can be used to validate relevant cardenolides in various biological samples and to infer chemical structures of unknown cardiac glycosides. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships which have, or could be perceived to have, influenced the work reported in this article. (© 2020 The Authors.) |
| Databáze: | MEDLINE |
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