A Metastatic Signet Ring Cell Carcinoma Presented as Acquired Thrombotic Thrombocytopenic Purpura: A Case Report.
| Autor: | Eisa N; Hematology Unit, Oncology Center, Mansoura University, Egypt., Nasef K; Medical Oncology Unit, Oncology Center, Mansoura University, Egypt., Emarah Z; Medical Oncology Unit, Oncology Center, Mansoura University, Egypt., Fattah MMA; Department of Pathology, Faculty of Medicine, Mansoura University, Egypt., Shamaa S; Medical Oncology Unit, Oncology Center, Mansoura University, Egypt. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of hematology [J Hematol] 2018 May; Vol. 7 (2), pp. 72-75. Date of Electronic Publication: 2018 May 10. |
| DOI: | 10.14740/jh386e |
| Abstrakt: | Microangiopathic hemolytic anemia (MAHA) may occur as a paraneoplastic syndrome in some solid tumors, but MAHA accompanied by signet ring cell carcinoma (SRCC) of an unknown origin is very rare. We report a patient who presented with an acute onset of Coombs negative hemolytic anemia and frequent schistocytes in the peripheral blood smear which are typical for MAHA as initial presentation of metastatic SRCC. Our patients fulfilled the criteria of thrombotic thrombocytopenic purpura (TTP) and received the specific treatment for TTP without improvement. Competing Interests: The authors have no conflict of interest. (Copyright 2018, Eisa et al.) |
| Databáze: | MEDLINE |
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