Plasma iron concentrations and systemic inflammatory response syndrome in neonatal foals.

Autor: Sanmartí J; Servei de Medicina Interna Equina, Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Barcelona, Spain.; Unitat Equina, Fundació Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Barcelona, Spain., Armengou L; Servei de Medicina Interna Equina, Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Barcelona, Spain.; Unitat Equina, Fundació Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Barcelona, Spain., Viu J; Servei de Medicina Interna Equina, Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Barcelona, Spain.; Hospital Veterinario Sierra de Madrid, 28750-San Agustín de Guadalix, Madrid, Spain., Alguacil E; Unitat Equina, Fundació Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Barcelona, Spain.; Uplands Way Vets Low Road, Bressingham, IP22 2AA Diss, Norfolk, UK., Civit S; Ganaderia JM, Barcelona, Spain., Ríos J; Unitat de Bioestadística, Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain., Jose-Cunilleras E; Servei de Medicina Interna Equina, Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Barcelona, Spain.; Unitat Equina, Fundació Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Barcelona, Spain.
Jazyk: angličtina
Zdroj: Journal of veterinary internal medicine [J Vet Intern Med] 2020 May; Vol. 34 (3), pp. 1325-1331. Date of Electronic Publication: 2020 Apr 16.
DOI: 10.1111/jvim.15770
Abstrakt: Background: Sparse information regarding plasma iron concentration in neonatal foals and its utility as an inflammatory marker in this population has been published.
Objectives: To determine the physiologic plasma iron concentration in neonatal foals. To assess its utility as an inflammatory marker to predict systemic inflammatory response syndrome (SIRS) and as a prognostic marker.
Animals: Forty-seven ill neonatal foals admitted to a referral equine hospital were divided in 2 groups based on the SIRS criteria (24 SIRS and 23 non-SIRS). Two control groups of 43 hospital and 135 stud farm healthy neonatal foals were also included.
Methods: Observational prospective study. Data were summarized by mean and its 95% confidence interval and absolute frequency and percentage for quantitative andqualitative variables. One-way ANOVA, ANCOVA (group and age effects) and Dunnett as posthoc analysis were used to compare plasma iron concentration among groups.
Results: Neonatal foals with SIRS did not have had any statistically significant different plasma iron concentrations compared to non-SIRS (P = .56) and stud farm control group (P = .99), 172.8 μg/dL (95% CI; 126.0-219.6), 193.1 μg/dL (139.1-247.2), and 181.8 μg/dL (171.3-192.4), respectively. Plasma iron concentration had a large variability in healthy neonatal foals, and was negatively correlated with age in hospital controls (rho = -0.387) and sick neonatal foals (rho = -0.598) (P < .001).
Conclusions and Clinical Importance: Plasma iron was not a useful marker of SIRS in neonatal foals and was not associated with outcome.
(© 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.)
Databáze: MEDLINE
Externí odkaz: