Quantitative measurement of atheroma burden: reproducibility in serial studies of atherosclerotic femoral arteries.

Autor: Wang Y; Department of Radiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 2006 Xiyuan Avenue, Chengdu, 611731, China. wangyuting_330@163.com.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA. wangyuting_330@163.com., Liu X; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.; Department of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China., Haraldsson H; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA., Zhu C; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA., Ballweber M; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA., Gasper W; Division of Vascular and Endovascular Surgery, University of California, San Francisco, CA, USA., Hatsukami T; Department of Surgery, University of Washington, Seattle, WA, USA., Saloner D; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Jazyk: angličtina
Zdroj: Magma (New York, N.Y.) [MAGMA] 2020 Dec; Vol. 33 (6), pp. 855-863. Date of Electronic Publication: 2020 Apr 16.
DOI: 10.1007/s10334-020-00843-7
Abstrakt: Objectives: This study aims to evaluate the reproducibility of measures of plaque morphology in serially acquired black-blood MRI of untreated atherosclerotic femoral arteries.
Materials and Methods: MR studies was obtained from 42 timepoints, on 12 patients with known femoral artery atherosclerosis. Images with a 3D isotropic FLASH with DANTE-prepared black blood contrast (DASH) at a 3-T scanner were acquired at baseline, within 1 week, and at 1 month. Six of the patients were scanned additionally at 6 months. Inter-scan and inter-observer variations of arterial area/volume measurements were evaluated.
Results: Measurement of vessel area, lumen area, wall area and wall volume showed inter-scan intraclass correlation coefficients (ICC) ranging from 0.92 to 0.97 for 3 scans, 0.91-0.97 for 4 scans, and inter-observer ICCs of 0.89-0.96. Among 3 scans, the coefficients of variance (CV) for the vessel area, lumen area, wall area and wall volume were 4.1%, 6.5%, 7.5%, and 4.4%. CVs among 4 scans ranged from 4.4% to 7.9%, and interobserver CVs ranged from 6.1% to 11.8% for the different area/volume measurements.
Conclusion: DASH MRI is useful for quantifying atherosclerotic vessel area and volume of femoral arteries with low variability among serial repeated scans and between observers.
Databáze: MEDLINE
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