Platelet-Rich plasma as an effective alternative approach for improving endometrial receptivity - a clinical retrospective study.

Autor: Frantz N; Nilo Frantz Medicina Reprodutiva, Porto Alegre, RS, Brazil., Ferreira M; Nilo Frantz Medicina Reprodutiva, Porto Alegre, RS, Brazil., Kulmann MI; Nilo Frantz Medicina Reprodutiva, Porto Alegre, RS, Brazil., Frantz G; Nilo Frantz Medicina Reprodutiva, Porto Alegre, RS, Brazil., Bos-Mikich A; Instituto Ciências Básicas da Saúde, Universidade Federal Do Rio Grande do Sul, Brazil., Oliveira R; RDO, Diagnósticos Médicos Ltda., São Paulo, SP, Brazil.
Jazyk: angličtina
Zdroj: JBRA assisted reproduction [JBRA Assist Reprod] 2020 Oct 06; Vol. 24 (4), pp. 442-446. Date of Electronic Publication: 2020 Oct 06.
DOI: 10.5935/1518-0557.20200026
Abstrakt: Objective: The aim of the present case series was to describe our experience with the use of PRP on patients with refractory thin endometria.
Methods: This retrospective analysis included 24 IVF cycles in which patients presenting different infertility factors received intrauterine PRP infusion prior to embryo transfer. Outcomes of interest were: clinical and ongoing pregnancies, miscarriages, and births.
Results: 54% of the cycles in which PRP was employed resulted in ongoing gestation or birth; 12.5% of the cycles ended in miscarriages.
Conclusion: Our data suggest that PRP improves intrauterine receptivity to embryo implantation, regardless of whether the endometrium reached the appropriate growth for embryo transfer.
Databáze: MEDLINE