Incidence of and Risk Factors for Lactational Mastitis: A Systematic Review.

Autor: Wilson E; London School of Hygiene and Tropical Medicine, London, UK.; University College London, University College, London, UK., Woodd SL; London School of Hygiene and Tropical Medicine, London, UK., Benova L; London School of Hygiene and Tropical Medicine, London, UK.; Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Jazyk: angličtina
Zdroj: Journal of human lactation : official journal of International Lactation Consultant Association [J Hum Lact] 2020 Nov; Vol. 36 (4), pp. 673-686. Date of Electronic Publication: 2020 Apr 14.
DOI: 10.1177/0890334420907898
Abstrakt: Background: Lactational mastitis is a maternal morbidity that affects the wellbeing of women and their babies, including through breastfeeding discontinuation.
Research Aim: To systematically review the available global literature on the frequency of lactational mastitis, and to summarize the evidence on risk factors for lactational mastitis. We also describe gaps in the evidence and identify priority areas for future research.
Methods: We systematically searched and screened 6 databases and included 26 articles, conducted meta-analysis of disease frequency, and narratively synthesized evidence on risk factors.
Results: In 11 (42%) articles researchers reported a measure of disease frequency; 5 (19%) reported risk factors, and 10 (39%) included both. Overall, the quality of studies was low, related to suboptimal measurement of disease frequency, high risk of bias, reverse causality, and incomplete adjustment for confounding. Meta-analysis was based on 3 studies (pooled incidence between birth and Week 25 postpartum: 11.1 episodes per 1,000 breastfeeding weeks; 95% CI [10.2-12.0]); with high heterogeneity across contexts and highest incidence in the first four weeks postpartum. Researchers assessed 42 potential risk factors; nipple damage was the most frequently studied and strongly associated with mastitis. There was a scarcity of studies from low-resource settings.
Conclusions: Lactational mastitis is a common condition, but the wide variability in incidence across contexts suggested that a substantial portion of this burden might be preventable. Provision of care to breastfeeding women at risk for or affected by mastitis is currently constrained due to a critical lack of high quality epidemiological evidence about its incidence and risk factors.
Databáze: MEDLINE