Demographic and clinical characteristics of familial and sporadic multiple sclerosis: A single center exploratory study from Abu Dhabi.

Autor: Ceccarelli A; Neurological Institute, Cleveland Clinic Abu Dhabi, Sowwah Square, Al Maryah Island, PO Box 112412, Abu Dhabi, United Arab Emirates. Electronic address: ceccarelli.antonella@gmail.com., Mifsud VA; Neurological Institute, Cleveland Clinic Abu Dhabi, Sowwah Square, Al Maryah Island, PO Box 112412, Abu Dhabi, United Arab Emirates., Dogar A; Neurological Institute, Cleveland Clinic Abu Dhabi, Sowwah Square, Al Maryah Island, PO Box 112412, Abu Dhabi, United Arab Emirates.
Jazyk: angličtina
Zdroj: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2020 Jun; Vol. 76, pp. 145-147. Date of Electronic Publication: 2020 Apr 10.
DOI: 10.1016/j.jocn.2020.04.007
Abstrakt: Demographic and clinical characteristics of Familial Multiple Sclerosis (FMS) have not been fully investigated yet in Abu Dhabi. The aim of this single center exploratory study was to investigate demographic and clinical characteristics of FMS compared to sporadic MS (SMS) in Abu Dhabi. A chart review single center study was conducted in 98 patients with MS. Group comparisons were performed using Mann-Whitney and Chi-Square tests as appropriate. A p < 0.05 was considered statistically significant. 24.5% were patients with FMS and 83% were Emirates. No significant differences in demographic and clinical characteristics were found between patients with FMS and SMS in overall all MS patients and in the Emirati group analyzed alone. Patients with FMS did not differ in demographic and clinical characteristics compared to patients with SMS. Further prospective studies are needed to elucidate environmental and genetic risk factors contributing to FMS in the Emirati population.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2020 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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