In vitro Antimicrobial Activity of Essential Oil Extracted from Leaves of Leoheo domatiophorus Chaowasku, D.T. Ngo and H.T. Le in Vietnam.
| Autor: | Trong Le N; Faculty of Pharmacy, Hue University of Medicine and Pharmacy, Hue University, Hue 49000, Vietnam., Viet Ho D; Faculty of Pharmacy, Hue University of Medicine and Pharmacy, Hue University, Hue 49000, Vietnam., Quoc Doan T; Faculty of Pharmacy, Hue University of Medicine and Pharmacy, Hue University, Hue 49000, Vietnam., Tuan Le A; Mientrung Institute for Scientific Research, VAST, Hue 49000, Vietnam., Raal A; Institute of Pharmacy, Faculty of Medicine, University of Tartu, 50900 Tartu, Estonia., Usai D; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Madeddu S; Department of Biomedical Science, University of Cagliari, 09042 Monserrato, CA, Italy., Marchetti M; CNR, Institute of Biomolecular Chemistry, Li Punti, 07100 Sassari, Italy., Usai M; Department of Chemistry and Pharmacy, University of Sassari, 07100 Sassari, Italy., Rappelli P; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Diaz N; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Zanetti S; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Nguyen HT; Faculty of Pharmacy, Hue University of Medicine and Pharmacy, Hue University, Hue 49000, Vietnam., Cappuccinelli P; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy., Donadu MG; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.; Department of Chemistry and Pharmacy, University of Sassari, 07100 Sassari, Italy. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Plants (Basel, Switzerland) [Plants (Basel)] 2020 Apr 03; Vol. 9 (4). Date of Electronic Publication: 2020 Apr 03. |
| DOI: | 10.3390/plants9040453 |
| Abstrakt: | : The present study aimed to determine the antimicrobial activity and chemical composition of leaves-extracted essential oil of Leoheo domatiophorus Chaowasku, D.T. Ngo and H.T. Le ( L. domatiophorus) , including antibacterial, antimycotic, antitrichomonas and antiviral effects. The essential oil was obtained using hydrodistillation, with an average yield of 0.34 ± 0.01% ( v/w , dry leaves). There were 52 constituents as identified by GC/MS with available authentic standards, representing 96.74% of the entire leaves oil. The essential oil was comprised of three main components, namely viridiflorene (16.47%), (-)-δ-cadinene(15.58%) and γ-muurolene (8.00%). The oil showed good antimicrobial activities against several species: Gram-positive strains: Staphylococcus aureus (two strains) and Enterococcus faecalis, with Minimum Inhibitory Concentration (MIC) and Minimum Lethal Concentration (MLC) values from 0.25 to 1% ( v/v ); Gram-negative strains such as Escherichia coli (two strains), Pseudomonas aeruginosa (two strains) and Klebsiella pneumoniae , with MIC and MLC values between 2% and 8% ( v/v ); and finally Candida species, having MIC and MLC between 0.12 and 4% ( v/v ).Antitrichomonas activity of the oil was also undertaken, showing IC Competing Interests: The authors declare that they have no conflicts of interest. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|