International expert consensus on the management of allergic rhinitis (AR) aggravated by air pollutants: Impact of air pollution on patients with AR: Current knowledge and future strategies.

Autor:	Naclerio R; Johns Hopkins School of Medicine, Baltimore, MD, USA., Ansotegui IJ; Department of Allergy & Immunology, Hospital Quironsalud Bizkaia- Bilbao, Spain., Bousquet J; INSERM U 1168, VIMA: Ageing and Chronic Diseases Epidemiological and Public Health Approaches, Villejuif, France.; University Versailles St-Quentin-en-Yvelines, France.; Allergy-Centre-Charité, Charité-Universita¨tsmedizin Berlin, Berlin, Germany., Canonica GW; Humanitas University & Research Hospital, Milano, Italy., D'Amato G; Division of Respiratory and Allergic Diseases, High Specialty Hospital A. Cardarelli, Napoli, Italy; School of Specialization in Respiratory Diseases University Federico II Naples, Italy., Rosario N; Pediatric Respiratory Medicine Division, Complexo Hospital de Clinicas, UFPR, Curitiba, Brazil., Pawankar R; Dept. of Pediatrics, Nippon Medical School, Tokyo, Japan., Peden D; UNC Center for Environmental Medicine, Asthma, and Lung Biology; Division of Allergy, Immunology and Rheumatology, Dpt. of Pediatrics UNS School of Medicine, USA., Bergmann KC; Allergy-Centre-Charité, Charité-Universita¨tsmedizin Berlin, Berlin, Germany., Bielory L; Medicine & Ophthalmology Hackensack Meridian School of Medicine at Seton Hall University Nutley, New Jersey, USA., Caraballo L; Institute for Immunological Research, University of Cartagena, Cartagena de Indias, Colombia., Cecchi L; Centre de Bioclimatology, University de Florence, Florence, Italy.; SOS Allergy and Immunology, Prato - USL Toscana Centro, Italy., Cepeda SAM; Fundación Hospital Universitario Metropolitano de Barranquilla, Barranquilla, Colombia., Chong Neto HJ; Federal University of Paraná, Brazil., Galán C; Department of Botany, Ecology and Plant Physiology, University of Córdoba, Spain., Gonzalez Diaz SN; San Francisco Centro de Especialistas Médicos Monterrey NL, Mexico., Idriss S; Department of Otolaryngology- Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon., Popov T; Alexander's University Hospital Clinic of Allergy & Asthma, Bulgaria., Ramon GD; Alergia e Inmunología, Hospital Italiano Regional del Sur, Bahía Blanca-Buenos Aires, Argentina., Ridolo E; Department of Clinical and Experimental Medicine, Università; di Parma, Parma, Italy., Rottem M; Allergy Asthma and Immunology, Emek Medical Center, Afula, Israel.; Rappaport Faculty of Medicine Technion, Israel Institute of Technology, Haifa, Israel., Songnuan W; Department of Plant Science, Faculty of Science, Mahidol University, Bangkok, Thailand.; Systems Biology of Diseases Research Unit, Faculty of Science, Mahidol University, Bangkok, Thailand., Rouadi P; Department of Otolaryngology- Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon.
Jazyk:	angličtina
Zdroj:	The World Allergy Organization journal [World Allergy Organ J] 2020 Apr 03; Vol. 13 (3), pp. 100106. Date of Electronic Publication: 2020 Apr 03 (Print Publication: 2020).
DOI:	10.1016/j.waojou.2020.100106
Abstrakt:	Allergic rhinitis affects the quality of life of millions of people worldwide. Air pollution not only causes morbidity, but nearly 3 million people per year die from unhealthy indoor air exposure. Furthermore, allergic rhinitis and air pollution interact. This report summarizes the discussion of an International Expert Consensus on the management of allergic rhinitis aggravated by air pollution. The report begins with a review of indoor and outdoor air pollutants followed by epidemiologic evidence showing the impact of air pollution and climate change on the upper airway and allergic rhinitis. Mechanisms, particularly oxidative stress, potentially explaining the interactions between air pollution and allergic rhinitis are discussed. Treatment for the management of allergic rhinitis aggravated by air pollution primarily involves treating allergic rhinitis by guidelines and reducing exposure to pollutants. Fexofenadine a non-sedating oral antihistamine improves AR symptoms aggravated by air pollution. However, more efficacy studies on other pharmacological therapy of coexisting AR and air pollution are currently lacking. Competing Interests: 1. Robert Naclerio: Lyra, Sanofi and Actos (Advisory Board; Speaker), Optinose. 2. Ignacio J Ansotegui.: No conflict of interest to declare. 3. Jean Bousquet: Chiesi, Cipla, Hikma, Menarini, Mundipharma, Mylan, Novartis, Sanofi-Aventis, Takeda, Teva, Uriach (Advisory Board, consultant, meeting lectures fees), Kyomed (shares). 4. Giorgio Walter Canonica: BI, ALK, Stallergens (Grant/research support), (Menarini, GSK, Sanofi, Teva, Hal, AZ, Novartis (honoraria or consultation fees). 5. Gennaro D'Amato: No conflict of interest to declare. 6. Nelson Rosario: MSD, GSK, Takeda, Sanofi, Danone, Novartis, Chiesi, AstraZeneca, Aché, FDA Allergenic, Boehringer Ingelheim (speaker); Takeda, MSD, Danone, Boehringer Ingelheim (written material); Danone, MEDA, Sanofi, Boehringer Ingelheim (Advisory). 7. Ruby Pawankar: No conflict of interest to declare. 8. David Peden: No conflict of interest to declare. 9. Karl-Christian Bergmann: No conflict of interest to declare. 10. Leonard Bielory: Allergy Therapeutics, Sanofi, Chattem (consultant), US EPA, CDC (Granta). 11. Luis Caraballo: No conflict of interest to declare. 12. Lorenzo Cecchi: No conflict of interest to declare. 13. S Alfonso M Cepeda: No conflict of interest to declare. 14. Herberto Jose Chong Neto: No conflict of interest to declare. 15. Carmen Galan: No conflict of interest to declare. 16. Sandra N Gonzalez Diaz: No conflict of interest to declare. 17. Samar Idriss: No conflict of interest to declare. 18. Todor A Popov.: No conflict of interest to declare. 19. German Dario Ramon: No conflict of interest to declare. 20. Erminia Ridolo: Faes Pharma (speaker). 21. Menachem Rottem: No conflict of interest to declare. 22. Wisuwat Songnuan: No conflict of interest to declare. 23. Philip Rouadi: GSK, MSD, Astra Zeneca, Bayer, Takeda, Novartis, Meda, Pharmaline, Algorithm, Abbott, Sanofi Pharmaceuticals (Speaker's Desk). (© 2020 The Authors.)
Databáze:	MEDLINE
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