Psychological distress and quality of life following positive fecal occult blood testing in colorectal cancer screening.

Autor: Vermeer NCA; Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands., van der Valk MJM; Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands., Snijders HS; Department of Surgery, Groene Hart ziekenhuis, Gouda, The Netherlands., Vasen HFA; Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands., Gerritsen van der Hoop A; Keizer Kliniek, Leiden University Medical Centre, Den Haag, The Netherlands., Guicherit OR; Department of Surgery, Haaglanden Medical Centre, Leidschendam, The Netherlands., Liefers GJ; Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands., van de Velde CJH; Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands., Stiggelbout AM; Medical Decision Making, Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, The Netherlands., Peeters KCMJ; Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
Jazyk: angličtina
Zdroj: Psycho-oncology [Psychooncology] 2020 Jun; Vol. 29 (6), pp. 1084-1091. Date of Electronic Publication: 2020 Apr 14.
DOI: 10.1002/pon.5381
Abstrakt: Objective: This study aimed to assess psychological functioning, quality of life, and regret about screening after a positive fecal immunochemical test (FIT) and subsequent colonoscopy, and to evaluate changes over time.
Methods: This is a prospective cohort study. Individuals aged 55 to 75 with a positive FIT that were referred for colonoscopy between July 2017 and November 2018, were invited to complete questionnaires related to psychological distress and health-related quality of life at three predefined time points: before colonoscopy, after histopathology result notification, and after 6 months. Four questionnaires were used: the Psychological Consequences Questionnaire (PCQ), the six-item Cancer Worry Scale (CWS), the Decision Regret Scale (DRS), and the 36-item Short-Form (SF-36).
Results: A total of 1066 participants out of 2151 eligible individuals were included. Patients with cancer showed a significant increase in psychological dysfunction (P = .01) and cancer worry (P = .008) after colonoscopy result notification, and a decline to pre-colonoscopy measurements after 6 months. In the no-cancer groups, psychological dysfunction and cancer worry significantly decreased over time (P < .05) but there was no ongoing decline. After 6 months, 17% of participants with no cancer experienced high level of cancer worry (CWS ≥ 10). Yet, only 5% reported high level of regret about screening participation (DRS > 25). A good global quality of life was reported in participants with no cancer.
Conclusion: Some psychological distress remains up to 6 months after colonoscopy in participants who tested false-positive in the Dutch bowel cancer screening program.
(© 2020 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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