Effect of the parasympathetic vasodilation on temperature regulation via trigeminal afferents in the orofacial area.

Autor: Ohke H; Division of Dental Anesthesiology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan., Sato T; Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan., Mito K; Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan., Terumitsu M; Division of Dental Anesthesiology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan., Ishii H; Division of Physiology, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan. hisayosh@hoku-iryo-u.ac.jp.
Jazyk: angličtina
Zdroj: The journal of physiological sciences : JPS [J Physiol Sci] 2020 Mar 31; Vol. 70 (1), pp. 22. Date of Electronic Publication: 2020 Mar 31.
DOI: 10.1186/s12576-020-00749-y
Abstrakt: The skin temperature (T m ) of the orofacial area influences orofacial functions and is related to the blood flow (BF). Marked increases in BF mediated by parasympathetic vasodilation may be important for orofacial T m regulation. Therefore, we examined the relationship between parasympathetic reflex vasodilation and orofacial T m in anesthetized rats. Electrical stimulation of the central cut end of the lingual nerve (LN) elicited significant increases in BF and T m in the lower lip. These increases were significantly reduced by hexamethonium, but not atropine. VIP agonist increased both BF and T m in the lower lip. The activation of the superior cervical sympathetic trunk (CST) decreased BF and T m in the lower lip; however, these decreases were significantly inhibited by LN stimulation. Our results suggest that parasympathetic vasodilation plays an important role in the maintaining the hemodynamics and T m in the orofacial area, and that VIP may be involved in this response.
Databáze: MEDLINE
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