[The human lectin supersystems possessing probiotic and protective actions.]

Autor: Lakhtin MV; G.N. Gabrichevsky Reseach Institute for Epidemiology & Microbiology, Moscow, Russia., Lakhtin VM; G.N. Gabrichevsky Reseach Institute for Epidemiology & Microbiology, Moscow, Russia., Mironov AY; G.N. Gabrichevsky Reseach Institute for Epidemiology & Microbiology, Moscow, Russia., Aleshkin VA; G.N. Gabrichevsky Reseach Institute for Epidemiology & Microbiology, Moscow, Russia., Afanasiev SS; G.N. Gabrichevsky Reseach Institute for Epidemiology & Microbiology, Moscow, Russia.
Jazyk: ruština
Zdroj: Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2020; Vol. 65 (4), pp. 231-238.
DOI: 10.18821/0869-2084-2020-65-4-231-238
Abstrakt: The potential of useful for human immunobiological supersystems of lectins (SSL) recognizing carbohydrates and glycoconjugates of molecular or supramolecular protein/(oligo)peptide-containing constituents of biotopes is described. SSL recognize, reversibly bind, delivery to biotopes, orient natural or synthetic polymeric, polyvalent glycoconjugates (imitators of natural glycopolymers) at the cell surface. The key features of SSL are indicated and described. The possibilities of application and prospects of SL of probiotics, complement С4 system and protein hormones (on example of erythropoietins) in prognostics and diagnostics of pathologies, prophylaxis and therapy of diseases and medical biotechnology are evaluated.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE