| Abstrakt: |
A study was made of indices of the erythron system in 137 alcoholic patients (stages I, II, III). At all 3 stages a rise of the level of intraerythrocytic 2,3-DPG in erythrocytes and a serum erythropoietic titer was detected, at II and III stages--reticulocytosis and erythrocytic life reduction, and at III stage--a decrease in the number of erythrocytes. The results indicated the involvement of the erythron system in the compensation of changes developing in alcoholism, first of all hypoxia. A possibility of the use of 2,3-DPG determination for the diagnosis of alcoholism and antihypoxic drugs in combined therapy of alcoholism was discussed. |
