The dilemma of diagnosing wound botulism in an infant: A rare case of paralysis with topical application of honey.
| Autor: | Mohd Tamrin MI; Surgical Department, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 Selangor, Malaysia. Electronic address: itamrin@upm.edu.my. |
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| Jazyk: | angličtina |
| Zdroj: | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2020 Jun; Vol. 95, pp. 157-159. Date of Electronic Publication: 2020 Mar 24. |
| DOI: | 10.1016/j.ijid.2020.03.044 |
| Abstrakt: | Botulism is a form of paralysis caused by a neurotoxin produced by the bacterium Clostridium botulinum. It is well known that natural honey contains Clostridium botulinum spores; controversy arises when a honey-related product is being used for wound care, where the possibility occurs of applying these spores to an open wound. To our knowledge, no reported cases of medical-grade honey have been associated with wound botulism. Given this fact, do we feel secure regarding the safety of this product, and will it be enough to alleviate our concern? We present a case of an infant with an infected umbilical stump, which required a surgical wound debridement. This infant developed a sudden progressive flaccid paralysis a few days after the application of topical medical grade honey for wound care. Even though suspicion of wound botulism is high, confirmation of the diagnosis, detection of neurotoxin, and isolating the organism remains a challenge. (Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.) |
| Databáze: | MEDLINE |
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