Two new 7, 20-epoxy- ent -kauranes from the aerial parts of Isodon eriocalyx .

Autor:	Li SY; Department of TCMs Pharmaceuticals, School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing, PR China., Zhu LH; Department of TCMs Pharmaceuticals, School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing, PR China.; Laboratory of Translational Medicine, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, PR China., Rao ZY; Institute of Drug Discovery, Hongyun Pharmaceutical Co., Ltd, Chengdu, PR China., Wang CJ; Institute of Drug Discovery, Hongyun Pharmaceutical Co., Ltd, Chengdu, PR China., Jiang M; Institute of Drug Discovery, Hongyun Pharmaceutical Co., Ltd, Chengdu, PR China., Zhang J; Laboratory of Translational Medicine, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, PR China., Yin ZQ; Department of TCMs Pharmaceuticals, School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing, PR China.
Jazyk:	angličtina
Zdroj:	Natural product research [Nat Prod Res] 2021 Nov; Vol. 35 (21), pp. 3859-3864. Date of Electronic Publication: 2020 Mar 25.
DOI:	10.1080/14786419.2020.1744141
Abstrakt:	Two previously undescribed 7, 20-epoxy- ent -kauranes along with six known ent -kauranoids, were isolated from the aerial parts of Isodon eriocalyx . The structures of new compounds were established on the basis of extensive spectroscopic analyses. Compound 2 could inhibit the production of interleukin - 1β (IL - 1β) in monosodium urate (MSU) and lipopolysaccharide (LPS) induced macrophages.
Databáze:	MEDLINE
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