Reactive Arthritis - A Rare Complication of Intravesical BCG Instillation.

Autor: Freixa M; Department of Internal Medicine, Hospital Pulido Valente, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal., Úria S; Department of Internal Medicine, Hospital Pulido Valente, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal., da Silva GN; Department of Internal Medicine, Hospital Pulido Valente, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.
Jazyk: angličtina
Zdroj: European journal of case reports in internal medicine [Eur J Case Rep Intern Med] 2020 Feb 04; Vol. 7 (3), pp. 001448. Date of Electronic Publication: 2020 Feb 04 (Print Publication: 2020).
DOI: 10.12890/2020_001448
Abstrakt: Reactive arthritis (ReA) with the classic triad of arthritis, conjunctivitis and urethritis, previously termed Reiter's syndrome, is a systemic illness, usually induced by genitourinary or gastrointestinal infections. However, it can be a rare complication of intravesical Bacillus Calmette-Guérin instillation (iBCG), a therapy prepared from attenuated strains of Mycobacterium bovis , a common and effective treatment for carcinoma in situ of the bladder (CisB). We report a case of a patient with CisB who developed ReA after iBCG. The symptoms resolved completely with corticosteroids. iBCG was stopped with no recurrence of carcinoma within 2 years.
Learning Points: ReA is an aseptic arthritis, usually triggered by genitourinary or gastrointestinal infections, generally in individuals positive for HLA-B27.Septic arthritis and microcrystalline arthritis can mimic ReA and they must be ruled out with arthrocentesis.ReA may be considered as a complication in patients under iBCG.
Competing Interests: Conflicts of Interests: The Authors declare that there are no competing interest
(© EFIM 2020.)
Databáze: MEDLINE