Contributions of the lupus register of the Spanish Society of Rheumatology (RELESSER) to the knowledge of systemic lupus erythematosus in Spain.

Autor: Rúa-Figueroa Fernández de Larrinoa I; Servicio de Reumatología, Hospital Universitario de Gran Canaria Doctor Negrín, Gran Canaria, España. Electronic address: iruafer@gobiernodecanarias.org., Pego-Reigosa JM; Servicio de Reumatología, Complejo Hospitalario Universitario de Vigo, Vigo, España.
Jazyk: English; Spanish; Castilian
Zdroj: Reumatologia clinica [Reumatol Clin (Engl Ed)] 2021 May; Vol. 17 (5), pp. 245-249. Date of Electronic Publication: 2020 Mar 21.
DOI: 10.1016/j.reuma.2020.01.006
Abstrakt: The lupus register of the Spanish Society of Rheumatology (RELESSER) is a multicentre register of patients with systemic lupus erythematosus (SLE) under follow-up by Spanish Rheumatology Services. It contains data on a total of 4024 patients with SLE. So far, 14 studies have been published from the transversal phase of RELESSER. Here we report the more relevant contributions of those studies, according to the authors' perspective, concerning cumulative clinical characteristics, level of activity, treatments, refractory disease, damage and mortality. We also review the main results of the analysis regarding incomplete SLE, lupus nephritis, respiratory manifestations, cardiovascular disease, serious infection, malignancies, fibromyalgia, SLE in males, SLE in Hispanics and juvenile-onset SLE, comparing the main characteristics of each subgroup to the global cohort. RELESSER has become one of the most important clinical SLE registers around the world, with a high yield in terms of knowledge generation about the disease in Spain, also useful for the entire scientific community.
(Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.)
Databáze: MEDLINE
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