A critical analysis of the impact of endocrine disruptors as a possible etiology of primary ovarian insufficiency.

Autor: Monteiro CS; Laboratory of Human Reproduction Professor Aroldo Fernando Camargos, Hospital das Clínicas, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Xavier EBS; Laboratory of Human Reproduction Professor Aroldo Fernando Camargos, Hospital das Clínicas, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.; Pro Criar, Medicina Reprodutiva, Belo Horizonte, MG, Brazil., Caetano JPJ; Pro Criar, Medicina Reprodutiva, Belo Horizonte, MG, Brazil., Marinho RM; Pro Criar, Medicina Reprodutiva, Belo Horizonte, MG, Brazil.; Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brazil.
Jazyk: angličtina
Zdroj: JBRA assisted reproduction [JBRA Assist Reprod] 2020 Jul 14; Vol. 24 (3), pp. 324-331. Date of Electronic Publication: 2020 Jul 14.
DOI: 10.5935/1518-0557.20200005
Abstrakt: Primary ovarian insufficiency is a cause of infertility that affects about 1% of women under 40 years old, and is considered as idiopathic in 75% of cases. This review aims to carry out a critical synthesis of the knowledge of the chemical agents likely to affect follicular stock in humans and / or animals, by direct toxicity to follicles, or by increasing their recruitments. For the majority of toxic agents, only experimental data are currently available. We propose a strategy to encourage progress in identifying occupational factors responsible for premature ovarian failure.
Databáze: MEDLINE