Sickle cell disease presenting in the third trimester of pregnancy: Delayed detection heralding a public health problem?
| Autor: | Sharma A; Senior Resident, Department of Pathology, Lady Hardinge Medical College, New Delhi, India., Gaur K; Assistant Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India., Tiwari VP; Associate Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India., Shukla S; Director Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India. |
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| Jazyk: | angličtina |
| Zdroj: | Indian journal of public health [Indian J Public Health] 2020 Jan-Mar; Vol. 64 (1), pp. 93-95. |
| DOI: | 10.4103/ijph.IJPH_223_19 |
| Abstrakt: | We report the case of a 22-year-old primigravida detected as having sickle cell disease (SCD), initially presenting in the third trimester (30 th week) of pregnancy. The patient came to our center with a complaint of severe lower limb pain. The peripheral smear showed marked anisopoikilocytosis, numerous leptocytes, sickle cells, and target cells. High-performance liquid chromatography corroborated the diagnosis of SCD, showing a significant peak in the sickle window. The patient was conservatively managed and delivered a healthy baby through normal vaginal delivery. Delayed presentation of SCD in the third trimester of pregnancy is unusual. This report aims to bring attention to the possible causes of such a lag in detection. We also suggest measures to refine the antenatal healthcare screening at multiple levels, with regard to the detection of sickle cell hemoglobinopathy. Competing Interests: None |
| Databáze: | MEDLINE |
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