PREVALENCE OF INSULIN RESISTANCE AND ASSOCIATION WITH METABOLIC RISK FACTORS AND FOOD CONSUMPTION IN ADOLESCENTS - RECIFE/BRAZIL.

Autor: Andrade MIS; Universidade Federal de Pernambuco, Recife, PE, Brazil., Oliveira JS; Universidade Federal de Pernambuco, Recife, PE, Brazil., Leal VS; Universidade Federal de Pernambuco, Recife, PE, Brazil., Lima NMDS; Universidade Federal de Pernambuco, Recife, PE, Brazil., Bezerra PB; Centro Universitário Maurício de Nassau, Recife, PE, Brazil., Santiago ERC; Universidade Federal de Pernambuco, Recife, PE, Brazil., Lira PIC; Universidade Federal de Pernambuco, Recife, PE, Brazil.
Jazyk: English; Portuguese
Zdroj: Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo [Rev Paul Pediatr] 2020 Mar 16; Vol. 38, pp. e2019016. Date of Electronic Publication: 2020 Mar 16 (Print Publication: 2020).
DOI: 10.1590/1984-0462/2020/38/2019016
Abstrakt: Objective: To identify the prevalence of insulin resistance in adolescents and its associations with metabolic factors and food intake.
Methods: Cross-sectional study conducted with a stratified, complex, school-based sample. The subjects were adolescents (n=1,081) who participated in the Study of Cardiovascular Risk in Adolescents in the city of Recife (Pernambuco, Brazil). We analyzed demographic, socioeconomic, behavioral, anthropometric, biochemical, and dietary variables. Insulin resistance was defined as HOMA-IR>75th percentile. A Poisson multivariate regression model with robust variance adjustment was used, and variables with p≤0.05 in the final model were considered statistically associated with insulin resistance.
Results: Median age was 14 years (interquartile range: 13-16 years), and 25.3% of the sample showed insulin resistance. The variables associated with insulin resistance in the final model were age, body mass index-for-age (BMI/A), biochemical markers (triglycerides and high-density lipoprotein cholesterol) and saturated fat intake, with insulin resistance being more prevalent in individuals whose consumption of this type of fat was below the median of the sample distribution.
Conclusions: Insulin resistance was prevalent in the adolescents analyzed and was significantly associated with metabolic variables and saturated fat intake.
Databáze: MEDLINE
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