Birth Registry of Women With Systematic Lupus Erythematosus: The Greek Experience.

Autor: Ntali S; Private Practice Rheumatologist, Thessaloniki, Greece., Pantazi L; Rheumatology Unit, GHA, Sismanogleio, Athens, Greece., Mpoki K; Rheumatology Unit, GHA, Sismanogleio, Athens, Greece., Nikolopoulos D; Rheumatology and Clinical Immunology Unit, 4 Internal Medicine University Clinic, GUH, Attikon, Athens, Greece., Fanouriakis A; Rheumatology and Clinical Immunology Unit, 4 Internal Medicine University Clinic, GUH, Attikon, Athens, Greece., Kallitsakis I; Private Practice Rheumatologist, Chania, Crete, Greece., Papagoras C; 1 University Internal Medicine Clinic, Medical School, DUT, Alexandroupolis, Greece., Dimopoulou D; 4 Internal Medicine Clinic, AUTH, Ippokrateio GHTH, Thessaloniki, Greece., Kteniadaki E; Private Practice Rheumatologist, Herakleion, Crete, Greece., Emmanouilidou E; Rheumatology and Clinical Immunology and Allergiology Clinic, PAGNI, Herakleion, Crete, Greece., Chania V; Rheumatology Unit, GHA, Sismanogleio, Athens, Greece., Bertsias G; Rheumatology and Clinical Immunology and Allergiology Clinic, PAGNI, Herakleion, Crete, Greece.
Jazyk: angličtina
Zdroj: Mediterranean journal of rheumatology [Mediterr J Rheumatol] 2018 Dec 18; Vol. 29 (4), pp. 228-231. Date of Electronic Publication: 2018 Dec 18 (Print Publication: 2018).
DOI: 10.31138/mjr.29.4.228
Abstrakt: Pregnancy in women with SLE (Systematic Lupus Erythematosus) is considered of "high risk" since it has been related with adverse events both in the mother and the foetus. Many studies have reported relapse of the disease during the pregnancy and the first trimester post-labour, while others have found no difference in terms of frequency and type of relapses. Moreover, adverse obstetrical events like recurrent pregnancy loss, preeclampsia, prematurity, intrauterine growth restriction and neonatal lupus syndrome tend to occur more often in patents with SLE. However, most of these data regarding the burden and pregnancy outcomes in SLE come from retrospective studies of previous decades, and in non-Caucasian patients. To this end, more recent studies have suggested overall improved outcomes of pregnancy, still their results are often conflicting. The purpose of this study is to record, through a prospective observational (non-interventional) study, the contemporary prognosis of pregnancy in women with SLE who are followed-up by private and hospital physicians in Greece. In particular, we aim to establish a registry to study the course of the disease during pregnancy, the outcome of pregnancy and the possible negative or positive prognostic factors, the effect of drugs on pregnancy and the foetus.
(© 2018 The Mediterranean Journal of Rheumatology (MJR).)
Databáze: MEDLINE