Application of Focal Photoinduced Thrombosis for Modeling Spinal Cord Ischemia.

Autor: Pashin SS; Department of Histology, Cytology and Embryology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia. pashinss@yandex.ru., Kuznetsov SL; Department of Histology, Cytology and Embryology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia., Pashina NR; Department of Histology, Cytology and Embryology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia., Tsomartova DA; Department of Histology, Cytology and Embryology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia., Chereshneva EV; Department of Histology, Cytology and Embryology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia., Ivanova MY; Department of Histology, Cytology and Embryology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2020 Feb; Vol. 168 (4), pp. 525-528. Date of Electronic Publication: 2020 Mar 16.
DOI: 10.1007/s10517-020-04746-4
Abstrakt: Typical ischemic damage to neurons were detected in the focus of experimental photothrombosis and in the transition zone. They were associated with symptoms of impaired motor functions and dysfunction of pelvic organs. The applied method of focal photothrombosis can be used for simulation of spinal cord ischemia for the development of methods for pharmacological correction and restoration of impaired sensorimotor functions.
Databáze: MEDLINE
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