Use of medication among nursing home residents: a Danish drug utilisation study.

Autor:	Lundby C; Hospital Pharmacy Funen, Odense University Hospital, Odense C, Denmark.; Clinical Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark, Odense C, Denmark., Jensen J; Type2dialog, Kongens Lyngby, Denmark., Larsen SP; Type2dialog, Kongens Lyngby, Denmark., Hoffmann H; Type2dialog, Kongens Lyngby, Denmark., Pottegård A; Hospital Pharmacy Funen, Odense University Hospital, Odense C, Denmark.; Clinical Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark, Odense C, Denmark., Reilev M; Clinical Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark, Odense C, Denmark.
Jazyk:	angličtina
Zdroj:	Age and ageing [Age Ageing] 2020 Aug 24; Vol. 49 (5), pp. 814-820.
DOI:	10.1093/ageing/afaa029
Abstrakt:	Background: Data on drug utilisation patterns in nursing home populations is scarce. We aimed to describe drug use patterns in Danish nursing home residents. Methods: We established a cohort of 5,179 individuals (63% women; median age of 84 years) admitted into 94 nursing homes across Denmark during 2015-2017. Data on prescription drug use and other census data were obtained from the nationwide Danish health registries. Results: The total number of drug classes filled increased from a median of 6 drugs (interquartile range [IQR] 3-9) at 18-24 months before nursing home admission to a median of 8 drugs (IQR 6-11) just after admission, with the most common drug classes comprising paracetamol (61%), platelet inhibitors (41%), proton pump inhibitors (34%), statins (33%) and potassium supplements (31%). The incidence rate of new drug treatments increased from 21 new treatments/100 residents/month at 12-24 months before admission to a peak of 71 new treatments/100 residents/month in the month prior to admission, while it levelled off to about 34 new treatments/100 residents/month after 6-9 months. The drug classes primarily responsible for this peak were laxatives, antibiotics and analgesics. The largest absolute increases were seen for laxatives (53%), paracetamol (43%) and antidepressants (36%), all showing a marked increase up to and following admission. A high proportion of residents remained on therapy in the 3-year period following admission, with users of antidepressants and antidementia drugs being most persistent. Conclusion: Nursing home admission is associated with an increase in use of both predominantly preventive and non-preventive drug classes. (© The Author(s) 2020. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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