A new formulation of polymer gel dosimeter with reduced toxicity: Dosimetric characteristics and radiological properties.

Autor: Rashidi A; Department of Radiation Medical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran., Abtahi SMM; Physics Department, Imam Khomeini International University, Qazvin, Iran. Electronic address: sm.abtahi@sci.ikiu.ac.ir., Saeedzadeh E; Department of Radiation Medical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran., Akbari ME; Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jazyk: angličtina
Zdroj: Zeitschrift fur medizinische Physik [Z Med Phys] 2020 Aug; Vol. 30 (3), pp. 185-193. Date of Electronic Publication: 2020 Mar 04.
DOI: 10.1016/j.zemedi.2020.02.002
Abstrakt: The present study aimed to produce a new, less toxic, and cost-effective polymer gel dosimeter using potassium salt of 2-acrylamido-2 methyl-propane sulfonic acid (AMPS) monomer. The new formulation was called PAKAG. The irradiation of PAKAG polymer gel dosimeter was performed using a 6 MV clinical linear accelerator, and its response was evaluated using magnetic resonance imaging. The obtained images were post-processed to produce related R 2 maps. Afterward, the Dose-R 2 calibration curves were obtained. Response dependence on the imaging temperature was examined. Furthermore, response stability over time was investigated. To investigate the radiological characteristics, the elemental composition, effective atomic number, electron density, and photon attenuation coefficient of PAKAG polymer gel dosimeter were calculated. A maximum sensitivity of 0.152±0.007 with the goodness of fit of R 2 =0.999 in a dynamic range of 0-6Gy at 12h post-irradiation time was found. Such as other polymer gel dosimeter, the response of PAKAG polymer gel dosimeter was dependent on post-irradiation time and imaging temperature. Finally, it was concluded that the PAKAG polymer gel dosimeter could be used as a less toxic and cost-effective polymer gel dosimeter.
(Copyright © 2020. Published by Elsevier GmbH.)
Databáze: MEDLINE
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