Arsenic and birth outcomes in a predominately lower income Hispanic pregnancy cohort in Los Angeles.
Autor: | Howe CG; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: caitlin.howe@usc.edu., Farzan SF; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: sffarzan@usc.edu., Garcia E; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: garc991@usc.edu., Jursa T; Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, 1156 High St, Santa Cruz, CA, 95064, USA. Electronic address: tpjursa@usc.edu., Iyer R; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr, Chicago, IL, 60611, USA. Electronic address: sarvesh@enmedmicroanalytics.com., Berhane K; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: kiros@usc.edu., Chavez TA; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: tachavez@usc.edu., Hodes TL; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: thodes@usc.edu., Grubbs BH; Department of Obstetrics and Gynecology, Keck School of Medicine, 2020 Zonal Ave, Los Angeles, CA, 90033, USA. Electronic address: brendan.grubbs@med.usc.edu., Funk WE; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr, Chicago, IL, 60611, USA. Electronic address: w-funk@northwestern.edu., Smith DR; Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, 1156 High St, Santa Cruz, CA, 95064, USA. Electronic address: drsmith@ucsc.edu., Bastain TM; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: bastain@usc.edu., Breton CV; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, 2001 N Soto St, Los Angeles, CA, 90032, USA. Electronic address: breton@usc.edu. |
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Jazyk: | angličtina |
Zdroj: | Environmental research [Environ Res] 2020 May; Vol. 184, pp. 109294. Date of Electronic Publication: 2020 Feb 27. |
DOI: | 10.1016/j.envres.2020.109294 |
Abstrakt: | Prenatal arsenic exposure has been associated with reduced fetal growth and increased risk for preterm birth, but most studies have been conducted in highly exposed populations outside the U.S. or in non-Hispanic populations in the rural U.S. The objectives of the current study were to: 1) examine the impact of early pregnancy exposure to arsenic on birth weight and gestational age at birth in a predominately lower income Hispanic pregnancy cohort in urban Los Angeles and 2) compare multiple biomarkers of arsenic exposure (blood, urine, and hair) assessed in early pregnancy (mean ± SD gestational age at biospecimen collection: 14 ± 4 weeks). Total arsenic (blood, hair) was measured by ICP-MS and speciated arsenic (urine) was measured by HPLC coupled to ICP-MS. Associations between log Competing Interests: Declaration of competing interest CGH, SFF, EG, TJ, RI, KB, TAC, TLH, BHG, DRS, TMB, and CVB declare no conflicts of interest. WEF is a founding partner in EnMed MicroAnalytics, a company that provides heavy metal screening for newborns and children. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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