| Autor: |
Sousa RDS; Department of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil., Oliveira FLC; Department of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil., Dias MRB; Department of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil., Minami NS; Department of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil., Amaral LD; Department of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil., Santos JAAD; Department of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil., Barrêto Júnior RA; Department of Animal Science, Federal Rural University of the Semiarid Region (UFERSA). Av. Francisco Mota, s/nº-Bairro Pres. Costa e Silva, Mossoró CEP 59625-900, RN, Brazil., Minervino AHH; Laboratory of Animal Health (LARSANA), Federal University of Western Pará (UFOPA) Rua Vera Paz, s/n, Salé, Santarém CEP 68040-255, PA, Brazil., Ortolani EL; Department of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil. |
| Abstrakt: |
The objective of this study was to characterize oligofructose-induced acute rumen lactic acidosis and its consequences in zebu cattle. We used 29 Nellore heifers which were submitted to experimental induction of laminitis by oligofructose excess. During the induction period, the animals underwent clinical examination, including laminitis diagnosis (hoof pressure testing and locomotion score) and blood and ruminal fluid sampling every six hours (over the initial 24 h) and every 12 h (up to 72 h), after the highest dose. Almost half of the animals (48.1%) required treatment with bicarbonate and saline to correct metabolic acidosis and dehydration. Due to this treatment, the animals were analyzed in treated (n = 13) and non-treated (n = 14) groups. The induction model promoted marked reduction in rumen pH, rumen anaerobiosis, carbon dioxide pressure, and increase in rumen lactate, blood osmolarity, and cortisol concentration. The animals treated had lower values of rumen pH and marked dehydration, evidenced by the increase in globular volume and serum urea. The clinical condition caused by excess oligofructose is severe, with the differential of the appearance of ephemeral fever and respiratory compensation against systemic acidosis, in addition to the frequent appearance of laminitis. |
