Complete reversal of constriction physiology with antitubercular treatment without steroid: a case report.

Autor:	Bagchi A; Department of Cardiology, Max Super Speciality Hospital, 1 & 2, Press Enclave Marg Saket District Centre, Saket Institutional Area Saket, New Delhi, Delhi 110017, India., Bhagwati M; Department of Cardiology, Max Super Speciality Hospital, 1 & 2, Press Enclave Marg Saket District Centre, Saket Institutional Area Saket, New Delhi, Delhi 110017, India., Rathi RK; Department of Cardiology, Max Super Speciality Hospital, 1 & 2, Press Enclave Marg Saket District Centre, Saket Institutional Area Saket, New Delhi, Delhi 110017, India.
Jazyk:	angličtina
Zdroj:	European heart journal. Case reports [Eur Heart J Case Rep] 2019 Oct 30; Vol. 3 (4), pp. 1-5. Date of Electronic Publication: 2019 Oct 30 (Print Publication: 2019).
DOI:	10.1093/ehjcr/ytz193
Abstrakt:	Background: Constrictive pericarditis is a chronic inflammation of the pericardium leading to the thickening of the pericardium that restricts cardiac filling. Globally tuberculosis is the commonest aetiology of constrictive pericarditis. Though normally considered to be an irreversible pathology; which requires surgical pericardiectomy, in early stage of the disease antitubercular therapy (ATT) along with steroids and other anti-inflammatory therapy can reverse the pathology. But, complete reversal of constrictive physiology with ATT without any anti-inflammatory drugs is not documented. Case Summary: Here, we describe a case where a 54-year-old lady presented with progressive dyspnoea and pedal oedema for 2 years along with anorexia and weight loss for two months. Two-dimensional echocardiography and computed tomography scan was suggestive of constrictive pericarditis. In view of systemic features and high acute phase reactants, patient was started on oral ATT without any steroids. After 4 months, constriction physiology was completely reversed. Discussion: Constriction physiology if treated timely can be largely reversed only with ATT without adjuvant anti-inflammatory therapy. Further studies are required to find out the specific indications of anti-inflammatory therapy in tubercular constrictive pericarditis. (© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.)
Databáze:	MEDLINE
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