Acute Myeloid Leukemia Presenting with Numb Chin Syndrome: A Case Report and Review of Literature.

Autor: Babikir MM; Department of Medical Education, Hamad Medical Corporation, Doha, Qatar., Mohamed SF; Department of Medical Oncology, Hematology Section, National Center for Cancer Care and Research (NCCCR), Hamad Medical Corporation, Doha, Qatar., Nashwan AJ; Nursing Education and Research Department, Hamad Medical Corporation, Doha, Qatar., Mudawi DS; Department of Medical Oncology, Hematology Section, National Center for Cancer Care and Research (NCCCR), Hamad Medical Corporation, Doha, Qatar., Purayil SC; Department of Medical Education, Hamad Medical Corporation, Doha, Qatar., Abdelrazek MT; Department of Radiology, Clinical Service Unit, Hamad Medical Corporation, Doha, Qatar., Ahmed KE; Department of Medical Education, Hamad Medical Corporation, Doha, Qatar., Yassin MA; Department of Medical Oncology, Hematology Section, National Center for Cancer Care and Research (NCCCR), Hamad Medical Corporation, Doha, Qatar.
Jazyk: angličtina
Zdroj: The American journal of case reports [Am J Case Rep] 2020 Mar 03; Vol. 21, pp. e920117. Date of Electronic Publication: 2020 Mar 03.
DOI: 10.12659/AJCR.920117
Abstrakt: BACKGROUND Numb chin syndrome is a rare and under diagnosed neuropathy of the inferior alveolar branch of the trigeminal nerve usually causing a lower lip and chin anesthesia or paresthesia. The syndrome is commonly associated with broad-spectrum malignant and non-malignant conditions. CASE REPORT Here we report a case of a 30-year-old male who presented with numb chin syndrome in the form of jaw pain, paresthesia, and hypoesthesia of the mental area as the presenting symptoms of acute of myeloid leukemia with t(8;21) treated with (3+7) protocol (3 days anthracycline+7 days cytarabine). The pain and paresthesia improved but hypothesia persisted. CONCLUSIONS Acute myeloid leukemia is one of the most serious causes of numb chin syndrome which should not be overlooked.
Databáze: MEDLINE
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