| Autor: |
Pa Pa Aung W; Department of Microbiology, University of Medicine 2, Yangon, Yangon, Myanmar., Myint NPST; Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar.; Insein General Hospital, Yangon, Myanmar., Zaw TT; Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar., Cooper DA; Myanmar Australia Research Collaboration for Health (MARCH), Yangon, Myanmar., Aung NM; Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar.; Insein General Hospital, Yangon, Myanmar., Kyi MM; Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar.; Insein General Hospital, Yangon, Myanmar., Lwin MM; Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar.; Department of Microbiology, University of Medicine 2, Yangon, Yangon, Myanmar., Hanson J; Myanmar Australia Research Collaboration for Health (MARCH), Yangon, Myanmar.; Department of Medicine, University of Medicine 2, Yangon, Yangon, Myanmar. |
| Abstrakt: |
The impact of HIV infection on the burden of gastrointestinal pathogens in Myanmar is poorly defined. Stools of 103 HIV-infected and 105 HIV-uninfected adult outpatients at a tertiary referral hospital in Yangon were examined microscopically. Stool antigen tests for Helicobacter pylori infection were positive in 63/103 (61%) HIV-infected and 61/105 (58%) HIV-uninfected patients ( P = 0.65). Soil-transmitted helminth infections were much less common, occurring in 9/103 (9%) HIV-infected and 13/103 (13%) HIV-uninfected patients ( P = 0.50). One HIV-uninfected patient had Giardia duodenalis , but there were no cases of Strongyloides stercoralis , Entamoeba histolytica , Capillaria philippinensis , Isospora , Cyclospora , or Schistosoma infection in the entire cohort. Despite the high prevalence of H. pylori , only 1/208 (0.5%) had ever received eradication, compared with 159/208 (76%) who had ever been dewormed. Helicobacter pylori appears to be an underappreciated pathogen in Myanmar. Its strong association with gastric cancer and peptic ulcer disease necessitates a more aggressive approach to its management. |
