Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review.

Autor: Biccas Neto L; Ocular Oftalmologia, Vitória, Brazil., Pulido JZ; Department of Oncology, Hospital Evangélico, Cachoeiro do Itapemirim, Brazil., Melo GB; Hospital de Olhos de Sergipe, Aracaju, Brazil.; Department of Ophthalmology, Universidade Federal de São Paulo, São Paulo, Brazil., Lima LH; Department of Ophthalmology, Universidade Federal de São Paulo, São Paulo, Brazil., Rodrigues EB; Department of Ophthalmology, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Ophthalmology, Saint Louis University School of Medicine, Saint Louis, MO, USA.
Jazyk: angličtina
Zdroj: Case reports in ophthalmological medicine [Case Rep Ophthalmol Med] 2020 Jan 30; Vol. 2020, pp. 6490535. Date of Electronic Publication: 2020 Jan 30 (Print Publication: 2020).
DOI: 10.1155/2020/6490535
Abstrakt: Colorectal cancer may yield metastasis to the choroid. Its management may be challenging, since there is no consensus about treatment. We describe a case of a 70-year-old male with colon cancer who complained of worsening visual acuity of his better-seeing eye to 20/40 secondary to a nonpigmented choroidal mass of medium reflectivity under the inferior temporal arcade and neurosensory foveal detachment. Besides systemic chemotherapy, local treatment with verteporfin photodynamic therapy (vPDT) was performed. After one month, visual acuity improved to 20/25 and subretinal fluid faded. In conclusion, vPDT may be a useful adjuvant treatment modality for choroidal metastasis secondary to colorectal cancer.
Competing Interests: The authors declare that there is no conflict of interest regarding the publication of this paper.
(Copyright © 2020 Laurentino Biccas Neto et al.)
Databáze: MEDLINE
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