Continuous Monitoring of Patient Mobility for 18 Months Using Inertial Sensors following Traumatic Knee Injury: A Case Study.

Autor:	Mueller A; Translational Medicine, Novartis Institutes for Biomedical Research, Forum 1, Novartis Campus, Basel, Switzerland., Hoefling H; NIBR Informatics, Novartis Institutes for Biomedical Research, Forum 1, Novartis Campus, Basel, Switzerland., Nuritdinow T; Sylvia Lawry Centre eV, The Human Motion Institute, Munich, Germany., Holway N; NIBR Informatics, Novartis Institutes for Biomedical Research, Forum 1, Novartis Campus, Basel, Switzerland., Schieker M; Translational Medicine, Novartis Institutes for Biomedical Research, Forum 1, Novartis Campus, Basel, Switzerland., Daumer M; TRIUM Online Analysis GmbH, Munich, Germany., Clay I; Translational Medicine, Novartis Institutes for Biomedical Research, Forum 1, Novartis Campus, Basel, Switzerland.
Jazyk:	angličtina
Zdroj:	Digital biomarkers [Digit Biomark] 2018 Aug 02; Vol. 2 (2), pp. 79-89. Date of Electronic Publication: 2018 Aug 02 (Print Publication: 2018).
DOI:	10.1159/000490919
Abstrakt:	Continuous patient activity monitoring during rehabilitation, enabled by digital technologies, will allow the objective capture of real-world mobility and aligning treatment to each individual's recovery trajectory in real time. To explore the feasibility and added value of such approaches, we present a case study of a 36-year-old male participant monitored continuously for activity levels and gait parameters using a waist-worn inertial sensor following a tibial plateau fracture on the right side, sustained as a result of a high-energy trauma during a sporting accident. During rehabilitation, data were collected for a period of 553 days, with > 80% daytime compliance, until the participant returned to near full mobility. The participant completed a daily diary with the annotation of major events (falls, near falls, cycling periods, or physiotherapy sessions) and key dates in the patient's recovery, including medical interventions, transitioning off crutches, and returning to work. We demonstrate the feasibility of collecting, storing, and mining of continuous digital mobility data and show that such data can detect changes in mobility and provide insights into long-term rehabilitation. We make both raw data and annotations available as a resource with the aspiration that further methods and insights will be built on this initial exploration of added value and continue to demonstrate that continuous monitoring can be deployed to aid rehabilitation. Competing Interests: Ieuan Clay and Martin Daumer are members of the editorial board for Karger Digital Biomarkers. Martin Daumer is Scientific Director of SLCMSR e.V. and CEO of Trium Analysis Online GmbH, makers of actibelt. (Copyright © 2018 by S. Karger AG, Basel.)
Databáze:	MEDLINE
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