Detection of Hepatitis B Surface Antigen among Febrile Patients in Ankpa, Kogi State, Nigeria.

Autor: Omatola CA; Department of Microbiology, Kogi State University, Anyigba P. M. B. 1008, Kogi State, Nigeria., Onoja BA; Department of Virology, University College Hospital, Ibadan, Oyo State, Nigeria., Agama J; Department of Microbiology, Kogi State University, Anyigba P. M. B. 1008, Kogi State, Nigeria.
Jazyk: angličtina
Zdroj: Journal of tropical medicine [J Trop Med] 2020 Feb 11; Vol. 2020, pp. 5136785. Date of Electronic Publication: 2020 Feb 11 (Print Publication: 2020).
DOI: 10.1155/2020/5136785
Abstrakt: Background: Hepatitis B virus (HBV) infection has become a significant public health problem in developing countries, and the high rate of morbidity and mortality from acute and chronic infections is worrisome. Therefore, this study determined the prevalence of HBV and associated risk factors in Ankpa, Kogi State, Nigeria. Materials and Methods . Sera randomly collected from 200 participants in three public hospitals in Ankpa were screened for HBsAg using commercially available HBsAg rapid test kit (Swe-Care (R), China). Structured questionnaires were used to obtain sociodemographic details and history of exposure to risk factors.
Results: Seventeen (8.5%) of the 200 patients were positive for HBsAg. Males had higher prevalence (10.89%) than females (6.06%). The age group with the highest rate of infection was 24-44 years. Patient's occupation and marital status were significantly higher in relation to HBsAg seropositivity. Risks of HBV infection in Ankpa are sharing of sharp objects (OR = 11.62, 95% CI, 3.59-37.59), multiple sexual partners (OR = 3.39, 95% CI, 1.23-9.38), blood transfusion (OR = 13.74, 95% CI, 4.22-44.71), surgeries (OR = 3.02, 95% CI, 1.03-8.83), alcoholism (OR = 6.94, 95% CI, 2.32-20.75), mouth-to-mouth kissing ( p =0.001), and contact with HBV patient (OR = 4.14, 95% CI, 1.01-17.06). People without prior knowledge of HBV infection were more infected.
Conclusion: This study reaffirms the endemicity of HBV in a part of sub-Saharan African country. Public health practitioners should focus attention on apparently healthy patients in developing countries. We suggest inclusion of HBsAg screening for patients coming for routine hospital care.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2020 Cornelius Arome Omatola et al.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje