What is the effect of the early follicular phase FSH/LH ratio on the number of mature oocytes and embryo development?
| Autor: | Arat Ö; Department of Obstetrics and Gynaecology, Fırat University School of Medicine, Elazığ, Turkey, Deveci D; Fırat University School of Health Services, Elazığ, Turkey, Özkan ZS; Department of Obstetrics and Gynaecology, Fırat University School of Medicine, Elazığ, Turkey; Department of Obstetrics and Gynaecology, Kırıkkale University School of Medicine, Kırıkkale, Turkey, Tuncer Can S; Department of Obstetrics and Gynaecology, Fırat University School of Medicine, Elazığ, Turkey |
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| Jazyk: | angličtina |
| Zdroj: | Turkish journal of medical sciences [Turk J Med Sci] 2020 Apr 09; Vol. 50 (2), pp. 420-425. Date of Electronic Publication: 2020 Apr 09. |
| DOI: | 10.3906/sag-1910-234 |
| Abstrakt: | Background/aim: Basal level of follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), and antral follicle count are used as predictors of ovarian reserve before starting ovulation induction. We aimed to investigate the predictor potential of early follicular phase FSH/LH ratio on controlled ovarian hyperstimulation-intracytoplasmic sperm injection (COH-ICSI) cycle outcomes. Materials and Methods: This retrospective cohort study was conducted with 648 COH-ICSI cycles performed between 2012 and 2014. Cycles were classified according to their basal FSH/LH ratio, group 1(G1) = FSH/LH ratio < 2, N = 473 and group 2(G2) = FSH/LH ratio ≥ 2, N = 175. Demographic characteristics and stimulation parameters were evaluated. Retrieved total oocyte count (TOC), mature oocyte count (MOC), transferred embryo number, and pregnancy results were obtained and transferred to computer by SPSS 21.0 programme. Results: TOC and MOC of G1 were significantly higher than those of G2. The total gonadotrophin doses of G2 were significantly higher than G1. There was no significant difference between groups for transferred embryo number. Pregnancy and live birth rates were similar in both groups. Conclusion: In our population, increased FSH/LH ratio did not affect the rates of pregnancy and live birth negatively. Competing Interests: The authors declare that there is no conflict of interest to disclose. (This work is licensed under a Creative Commons Attribution 4.0 International License.) |
| Databáze: | MEDLINE |
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