Self-reported negative outcomes of psilocybin users: A quantitative textual analysis.

Autor: Bienemann B; Department of Psychology, Pontifícia Universidade Católica, São Paulo, Brazil., Ruschel NS; Department of Psychology, Pontifícia Universidade Católica, São Paulo, Brazil., Campos ML; Department of Psychology, Pontifícia Universidade Católica, São Paulo, Brazil., Negreiros MA; Department of Psychology, Pontifícia Universidade Católica, São Paulo, Brazil., Mograbi DC; Department of Psychology, Pontifícia Universidade Católica, São Paulo, Brazil.; Department of Psychology, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, England, United Kingdom.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2020 Feb 21; Vol. 15 (2), pp. e0229067. Date of Electronic Publication: 2020 Feb 21 (Print Publication: 2020).
DOI: 10.1371/journal.pone.0229067
Abstrakt: Psilocybin, a substance mainly found in mushrooms of the genus psilocybe, has been historically used for ritualistic, recreational and, more recently, medicinal purposes. The scientific literature suggests low toxicity, low risk of addiction, overdose, or other causes of injury commonly caused by substances of abuse, with growing interest in the use of this substance for conditions such as treatment-resistant depression. However, the presence of negative outcomes linked to psilocybin use is not clear yet. The objective of this study is to investigate the negative effects of psilocybin consumption, according to the users' own perception through self-reports extracted from an online platform. 346 reports were analyzed with the assistance of the IRAMUTEQ textual analysis software, adopting the procedures of Descending Hierarchical Classification, Correspondence Factor Analysis and Specificities Analysis. The text segments were grouped in 4 main clusters, describing thinking distortions, emergencies, perceptual alterations and the administration of the substance. Bad trips were more frequent in female users, being associated with thinking distortions. The use of multiple doses of psilocybin in the same session or its combination with other substances was linked to the occurrence of long-term negative outcomes, while the use of mushrooms in single high doses was linked to medical emergencies. These results can be useful for a better understanding of the effects of psilocybin use, guiding harm-reduction initiatives.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje