Costus afer : A Systematic Review of Evidence-Based Data in support of Its Medicinal Relevance.

Autor: Boison D; Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana., Adinortey CA; Department of Molecular Biology and Biotechnology, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana., Babanyinah GK; Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana., Quasie O; Centre for Plant Medicine Research, Mampong-Akuapem, Ghana., Agbeko R; Department of Molecular Biology and Biotechnology, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana., Wiabo-Asabil GK; Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana., Adinortey MB; Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
Jazyk: angličtina
Zdroj: Scientifica [Scientifica (Cairo)] 2019 Dec 25; Vol. 2019, pp. 3732687. Date of Electronic Publication: 2019 Dec 25 (Print Publication: 2019).
DOI: 10.1155/2019/3732687
Abstrakt: Costus afer ( C. afer ) is a plant commonly known as ginger lily, spiral ginger, or bush cane. It is reportedly used in traditional medicine practice (TMP) to treat and manage many ailments including diabetes mellitus, stomach ache, arthritis, inflammation, and gout. These purported ethnomedicinal uses have triggered many research studies on the plant to amass scientific evidence. However, these research reports are scattered, and thus, this systematic review seeks to provide a comprehensive update on it covering its traditional uses, phytochemical and nutritional constituents, pharmacological activities, and toxicological effects. An online search was done using search engines such as Google Scholar, PubMed, and ScienceDirect from the period 1970 to 2019. The online search included the use of keywords, " Costus afer Ker-Gawl" or " Costus afer ." The search revealed that the stem and leaves of the plant contain substantial amounts of micronutrients and macronutrients. The leaves, stem, rhizomes, and roots of C. afer contain several steroidal sapogenins, aferosides, dioscin, and paryphyllin C and flavonoid glycoside kaempferol-3-O- α -L-rhamnopyranoside. Experimental studies on various parts of the plant showed bioactivities such as antihyperglycemic, hepatocellular protection, cardioprotection, nephroprotection, testicular protection, CNS depressant, analgesic, antiarthritis, antibacterial, and antioxidant. Based on these evident data, it is concluded that the plant could be used as an alternative and complementary therapy for many oxidative stress-related diseases, provided further scientific studies on the toxicological and pharmacological aspects are carried out.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2019 Daniel Boison et al.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje