Advanced spheroidal degeneration.

Autor: Elhusseiny AM; Department of Ophthalmology, Kasr Al-Ainy Hospitals, Cairo University, Giza, Egypt., El Sheikh RH; Department of Ophthalmology, Kasr Al-Ainy Hospitals, Cairo University, Giza, Egypt., Jamerson E; Department of Ophthalmology, Columbia University Medical Center, New York., Swaify IY; Department of Ophthalmology, Kasr Al-Ainy Hospitals, Cairo University, Giza, Egypt., Araissi AB; Department of Ophthalmology, Kasr Al-Ainy Hospitals, Cairo University, Giza, Egypt., Saad AA; Department of Ophthalmology, Kasr Al-Ainy Hospitals, Cairo University, Giza, Egypt.
Jazyk: angličtina
Zdroj: Digital journal of ophthalmology : DJO [Digit J Ophthalmol] 2019 Dec 22; Vol. 25 (4), pp. 68-71. Date of Electronic Publication: 2019 Dec 22 (Print Publication: 2019).
DOI: 10.5693/djo.02.2019.11.001
Abstrakt: Spheroidal degeneration, involving the cornea and/or the conjunctiva, is characterized by amber-colored homogeneous, translucent spherules in the corneal stroma, Bowman's membrane, and subepithelium. The condition has a higher prevalence in areas with extreme temperatures, low humidity, high wind, and presence of sand. We report the case of a 46-year-old man with a 10-year history of gradual progressive diminution of vision, severe blepharospasm, and photophobia. Examination revealed bilateral plaques of amber-colored nodules covering about half of the cornea. Superficial keratectomy was performed for the lesions in both eyes, leaving an epithelial defect overlying a plane of opaque cornea. Histopathology showed amorphous protein in the anterior stroma, confirming the clinical diagnosis of advanced grade 4 spheroidal degeneration. Visual acuity and other symptoms dramatically improved, and the patient was scheduled for keratoplasty.
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Databáze: MEDLINE
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