Tropheryma whipplei endocarditis: An uncommon infection with potentially fatal consequences.

Autor: Muretti M; Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Keiralla A; Department of Cardiothoracic Anesthesia, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Jeffery K; Department of Microbiology and Infectious Diseases, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Krasopoulos G; Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.; Department of Cardiothoracic Surgery, University of Oxford, Oxford, United Kingdom.
Jazyk: angličtina
Zdroj: Journal of cardiac surgery [J Card Surg] 2020 Apr; Vol. 35 (4), pp. 923-925. Date of Electronic Publication: 2020 Feb 14.
DOI: 10.1111/jocs.14467
Abstrakt: We report a case of culture-negative aortic valve endocarditis secondary to Tropheryma whipplei infection. Our patient underwent aortic valve replacement after 4 weeks of antibiotic therapy with persistently negative blood culture results. Despite a technically uneventful operation, the patient showed continued sepsis and was unresponsive to a broad-spectrum of antibiotic therapy with subsequent multiorgan failure. He died on the 5th postoperative day, and diagnosis was established at postmortem examination. In this case report, we discuss the diagnosis and treatment of a rare type of endocarditis caused by T. whipplei.
(© 2020 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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