Epidemiologic Features of Systemic Vasculitides in the Southeast Region of Brazil: Hospital-Based Survey.

Autor:	Belem JMFM; From the Rheumatology Division, Department of Medicine, Universidade Federal de São Paulo-Escola Paulista de Medicina (Unifesp-EPM)., Pereira RMR; Rheumatology Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP., Perez MO; Rheumatology Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP., do Prado LL; Rheumatology Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP., Calich AL; From the Rheumatology Division, Department of Medicine, Universidade Federal de São Paulo-Escola Paulista de Medicina (Unifesp-EPM)., Sachetto Z; Rheumatology Division, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Campinas, SP., Bacchiega ABS; Rheumatology Division, Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ., Simil FF; Departamento do Aparelho Locomotor, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG., Pedreira AL; Serviço de Reumatologia do Hospital Universitário Professor Edgar Santos (HUPES), Salvador, BA., Gazzeta MO; Hospital Federal dos Servidores do Estado do Rio de Janeiro (HFSE-RJ), Rio de Janeiro, RJ., Dinis VG; Rheumatology Division, Department of Internal Medicine, Universidade Federal do Espírito Santo (UFES), Vitória, ES., Mariz HA; Rheumatology Division, Universidade Federal de Pernambuco (UFPE), Recife, PE., Duque RH; Rheumatology Division, Department of Internal Medicine, Universidade Federal do Espírito Santo (UFES), Vitória, ES., Schau B; Hospital Federal dos Servidores do Estado do Rio de Janeiro (HFSE-RJ), Rio de Janeiro, RJ., Santiago MB; Serviço de Reumatologia do Hospital Universitário Professor Edgar Santos (HUPES), Salvador, BA., Ferreira GA; Departamento do Aparelho Locomotor, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG., Ochtrop MLG; Rheumatology Division, Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ., Gonçalves CR; Rheumatology Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP., Rêgo J; Rheumatology Division, Universidade Federal de Goiás (UFG), Goiânia, GO, Brazil., Levy RA; UERJ (Licensed), Global Medical Expert, Immunology and Specialty Pharma, GSK, Collegeville, PA., de Souza AWS; From the Rheumatology Division, Department of Medicine, Universidade Federal de São Paulo-Escola Paulista de Medicina (Unifesp-EPM).
Jazyk:	angličtina
Zdroj:	Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases [J Clin Rheumatol] 2020 Oct; Vol. 26 (7S Suppl 2), pp. S106-S110.
DOI:	10.1097/RHU.0000000000001041
Abstrakt:	Background/objective: The epidemiology of vasculitis is variable in different geographic areas, and this issue has not been approached in Brazil yet. The objective of this study was to assess the frequency of vasculitis in specialized centers in Brazil. Methods: This cross-sectional study was performed in 9 vasculitis outpatient clinics from 6 different states mainly from the Southeast and the Northeast regions of Brazil between 2015 and 2017. Diagnosis and/or classification criteria for Behçet disease (BD), Takayasu arteritis (TA), giant cell arteritis (GCA), polyarteritis nodosa (PAN), granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis with polyangiitis (EGPA), and cryoglobulinemic vasculitis (CryoVas) were used to include patients with at least 6 months of follow-up in this hospital-based survey. Results: A total of 1233 patients with systemic vasculitis were included from the Southeast region. Behçet disease was the most frequent vasculitis (35.0%) followed by TA (26.4%), GPA (16.2%), PAN (5.8%), GCA (5.8%), EGPA (4.3%), MPA (3.4%), and CryoVas (3.0%). Up to 7.8% of vasculitis patients had a juvenile onset, and the frequency of vasculitides found in children and adolescents was as follows: TA (52.6%), BD (24.7%), GPA (12.4%), and PAN (10.3%). No cases of EGPA, MPA, and CryoVas were diagnosed before the age of 18 years. As a comparator, 103 vasculitis patients were included in the Northeast of Brazil where TA was found in 36.9% and BD in 31.1% of vasculitis cases. No GCA cases were found in the Northeast part of Brazil. Conclusions: Similar to the epidemiology of vasculitis in Asia, BD and TA are the most frequent vasculitis in Southeastern Brazilian referral centers.
Databáze:	MEDLINE
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