Locally advanced rectal cancer: 3D diffusion-prepared stimulated-echo turbo spin-echo versus 2D diffusion-weighted echo-planar imaging.

Autor: Zhang Q; Amsterdam UMC, Radiology and Nuclear Medicine, University of Amsterdam, Room Z0-178, Meibergdreef 9, 1100 DD, Amsterdam, Netherlands. q.zhang@amsterdamumc.nl., van Houdt PJ; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands., Lambregts DMJ; Department of Radiology, Netherlands Cancer Institute, Amsterdam, Netherlands., van Triest B; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands., Kop MPM; Amsterdam UMC, Radiology and Nuclear Medicine, University of Amsterdam, Room Z0-178, Meibergdreef 9, 1100 DD, Amsterdam, Netherlands., Coolen BF; Amsterdam UMC, Biomedical Engineering and Physics, University of Amsterdam, Amsterdam, the Netherlands., Strijkers GJ; Amsterdam UMC, Biomedical Engineering and Physics, University of Amsterdam, Amsterdam, the Netherlands., van der Heide UA; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands., Nederveen AJ; Amsterdam UMC, Radiology and Nuclear Medicine, University of Amsterdam, Room Z0-178, Meibergdreef 9, 1100 DD, Amsterdam, Netherlands.
Jazyk: angličtina
Zdroj: European radiology experimental [Eur Radiol Exp] 2020 Feb 07; Vol. 4 (1), pp. 9. Date of Electronic Publication: 2020 Feb 07.
DOI: 10.1186/s41747-019-0138-x
Abstrakt: Background: Diffusion-weighted imaging (DWI) has shown great value in rectal cancer imaging. However, traditional DWI with echo-planar imaging (DW-EPI) often suffers from geometrical distortions. We applied a three-dimensional diffusion-prepared stimulated-echo turbo spin-echo sequence (DPsti-TSE), allowing geometrically undistorted rectal DWI. We compared DPsti-TSE with DW-EPI for locally advanced rectal cancer DWI.
Methods: For 33 prior-to-treatment patients, DWI images of the rectum were acquired with DPsti-TSE and DW-EPI at 3 T using b-values of 200 and 1000 s/mm 2 . Two radiologists conducted a blinded scoring of the images considering nine aspects of image quality and anatomical quality. Tumour apparent diffusion coefficient (ADC) and distortions were compared quantitatively.
Results: DPsti-TSE scored significantly better than DW-EPI in rectum distortion (p = 0.005) and signal pileup (p = 0.001). DPsti-TSE had better tumour Dice similarity coefficient compared to DW-EPI (0.84 versus 0.80, p = 0.010). Tumour ADC values were higher for DPsti-TSE compared to DW-EPI (1.47 versus 0.86 × 10 -3 mm 2 /s, p < 0.001). Radiologists scored DPsti-TSE significantly lower than DW-EPI on aspects of overall image quality (p = 0.001), sharpness (p < 0.001), quality of fat suppression (p < 0.001), tumour visibility (p = 0.009), tumour conspicuity (p = 0.010) and rectum wall visibility (p = 0.005).
Conclusions: DPsti-TSE provided geometrically less distorted rectal cancer diffusion-weighted images. However, the image quality of DW-EPI over DPsti-TSE was referred on the basis of several image quality criteria. A significant bias in tumour ADC values from DPsti-TSE was present. Further improvements of DPsti-TSE are needed until it can replace DW-EPI.
Databáze: MEDLINE
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